Christa S Zerbe Selected Research

GATA2 Deficiency

1/2021	Hematopoietic Cell Transplantation and Outcomes Related to Human Papillomavirus Disease in GATA2 Deficiency.
1/2018	Allogeneic Hematopoietic Stem Cell Transplantation for GATA2 Deficiency Using a Busulfan-Based Regimen.
1/2018	Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.
1/2016	Association of GATA2 Deficiency With Severe Primary Epstein-Barr Virus (EBV) Infection and EBV-associated Cancers.
2/2014	GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity.
5/2013	GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome.
9/2011	Successful allogeneic hematopoietic stem cell transplantation for GATA2 deficiency.

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Christa S Zerbe Research Topics

Disease

14	Infections 04/2022 - 08/2005
12	Chronic Granulomatous Disease 04/2022 - 02/2012
7	GATA2 Deficiency 01/2021 - 09/2011
4	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2021 - 01/2018
2	Mycoses (Diseases, Fungus) 01/2022 - 01/2017
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 01/2021
2	Bone Marrow Failure Disorders 01/2021 - 01/2018
2	Neoplasms (Cancer) 01/2021 - 04/2013
2	Persistent Infection 01/2020 - 10/2012
2	Liver Abscess 01/2018 - 03/2012
2	Chronic Mucocutaneous Candidiasis 04/2016 - 06/2013
2	Reinfection 03/2016 - 04/2015
2	Histoplasmosis 01/2016 - 06/2013
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 08/2022
1	Bacterial Infections (Bacterial Infection) 04/2022
1	Fever (Fevers) 04/2022
1	Neutropenia 04/2022
1	Febrile Neutropenia 04/2022
1	Leigh Disease (Leigh's Disease) 01/2022
1	Herpes Zoster 11/2021
1	Chickenpox 11/2021
1	Pulmonary Alveolar Proteinosis 10/2021
1	Pulmonary Hypertension 10/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021
1	deficiency receptor 1 Interferon gamma 10/2020
1	Primary Immunodeficiency Diseases 01/2020
1	Disease Progression 01/2020
1	Abscess 01/2018
1	Leukocyte adhesion deficiency type 1 01/2017
1	Pediatric Crohn's disease 12/2016
1	Tuberculosis (Tuberculoses) 03/2016
1	Colitis 06/2015
1	Mucormycosis 07/2014
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 02/2014
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2014
1	Lymphedema (Milroy Disease) 02/2014
1	Coccidioidomycosis 06/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 05/2013
1	Opportunistic Infections (Opportunistic Infection) 04/2013
1	Lymphopenia (Lymphocytopenia) 04/2013
1	Pneumonia (Pneumonitis) 02/2012
1	Inborn Genetic Diseases (Disease, Hereditary) 02/2012
1	Pancytopenia 09/2011
1	Nephrotic Syndrome (Syndrome, Nephrotic) 09/2011
1	Osteomyelitis 08/2005

Drug/Important Bio-Agent (IBA)

5	Anti-Bacterial Agents (Antibiotics)IBA 04/2022 - 02/2012
5	AutoantibodiesIBA 11/2021 - 03/2016
4	InterferonsIBA 01/2021 - 08/2005
4	STAT1 Transcription FactorIBA 01/2018 - 06/2013
3	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022 - 05/2013
3	Interferon-gamma (Interferon, gamma)IBA 01/2021 - 01/2016
2	Busulfan (Busulfex)FDA Link 01/2020 - 01/2018
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2020 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2016
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018 - 03/2012
2	ruxolitinibIBA 01/2018 - 01/2017
2	NADP (NADPH)IBA 01/2018 - 04/2015
2	Amphotericin B (Amphotericin)FDA LinkGeneric 03/2017 - 10/2012
2	Interleukin-12 (IL 12)IBA 01/2017 - 06/2013
2	Superoxides (Superoxide)IBA 12/2016 - 02/2012
2	GATA2 Transcription FactorIBA 02/2014 - 04/2013
1	Messenger RNA (mRNA)IBA 08/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 04/2022
1	Alemtuzumab (Campath)FDA Link 04/2022
1	Ustekinumab (CNTO 1275)FDA Link 01/2022
1	RotenoneIBA 01/2022
1	Rituximab (Mabthera)FDA Link 01/2021
1	daratumumabIBA 01/2021
1	Bortezomib (Velcade)FDA Link 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2020
1	Pentostatin (Nipent)FDA LinkGeneric 01/2020
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2018
1	5' Untranslated Regions (5' UTR)IBA 01/2018
1	Methotrexate (Mexate)FDA LinkGeneric 01/2018
1	Janus Kinase InhibitorsIBA 01/2017
1	Janus KinasesIBA 01/2017
1	Interleukin-23 (Interleukin 23)IBA 01/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016
1	CytokinesIBA 01/2016
1	NF-kappa B (NF-kB)IBA 01/2016
1	Pioglitazone (Actos)FDA Link 11/2015
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 06/2015
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 06/2015
1	Oxidoreductases (Dehydrogenase)IBA 04/2015
1	ElementsIBA 05/2013
1	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 05/2013
1	Voriconazole (Vfend)FDA LinkGeneric 10/2012
1	Itraconazole (Sporanox)FDA LinkGeneric 10/2012
1	Interferon gamma ReceptorIBA 08/2005

Therapy/Procedure

5	Transplantation 04/2022 - 09/2011
4	Therapeutics 04/2022 - 03/2012
3	Cell Transplantation 04/2022 - 01/2020
3	Hematopoietic Stem Cell Transplantation 10/2021 - 09/2011
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 10/2020 - 01/2020
1	Stem Cell Transplantation 10/2021
1	Enteral Nutrition (Feeding, Tube) 01/2021